IPEC e-newsletter - Excipients Insight October 2017 - 16-10-17


Inside this issue


Recommended reading

A multifunctional mineral excipient

Orally disintegrating tablets (ODTs) are becoming increasingly important in the global pharmaceutical market for both prescription and over-the-counter medications because they can significantly improve patient compliance. They can be swallowed without the need for water, are generally smaller, and have good mouthfeel. Such properties make ODTs particularly convenient for children and the elderly, especially when a flavor is also incorporated into the formulation. In addition, they are the delivery format of choice for people who want to take their medicine “on the go” and are particularly helpful for patients who have difficulty swallowing--a complication associated with a number of age-related conditions, including stroke and Parkinson’s disease.


Using Quality by Design in the formulation of tablets and capsules

This article discusses the types of supporting activities and scale of operations that will help you get a new product filing accepted and eventually approved by the regulatory authorities.

Tablets & Capsules (Registration required)

Applying QbD in process development

Over the past few years, global regulatory authorities have been raising the expectation of incorporating quality by design (QbD) into pharmaceutical development. While QbD offers many important long-term benefits, these expectations are having a dramatic impact on product development groups and their supporting corporate informatics infrastructure. This article discusses how QbD requirements for risk assessment, process assessment, material assessment, documentation, and traceability can be addressed with informatics, using development of an impurity control strategy as an example.


Eye on Excipients: Taste modulation

This edition of the column discusses the genesis and development of ClearTaste, a novel taste-modulating excipient based on the use of solid-state myceliation.

Tablets & Capsules (Registration required)




Copyright © 2005 - 2018 IPEC Europe - International Pharmaceutical Excipients Council