IPEC e-newsletter - Excipients Insight July/August 2018 - 31-08-18


Inside this issue


EFSA says it does not need to reopen opinion on TiO2 safety

In May, France’s National Assembly passed an amendment banning the use, import and marketing of any food product containing titanium dioxide (TiO2) as a food additive.

The amendment was passed as a component of France’s farm and food bill and as a consequence some food and confectionary manufacturers have already pledged to phase out the use of TiO2 by 2020. The final vote on the law was due as this edition of Excipients Insight went to press.

The debate about the safety of the ingredient, which is also used in pharmaceutical preparations as an excipient, stems from a 2017 French scientific study highlighted the potential carcinogen risks of nanoparticles of Ti02. However, the European Food Safety Authority (EFSA) stated in 2016 that Ti02 poses no health concerns – a position that it reiterated in July after being requested by the European Commission to look again into the data available on the ingredient.

“Altogether, the panel concluded that the outcome of the four studies did not merit re-opening the existing opinion of EFSA related to the safety of TiO2 (E 171) as a food additive,” says the EFSA in its report.

The assessors “considered that the four studies evaluated, highlighted some concerns but with uncertainties, therefore their relevance for the risk assessment was considered limited and further research would be needed to decrease the level of uncertainties.”




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